During stage I entitled: “Synthesis and characterization of the precursors for the further preparation of N / MPs” several activities were carried out as follows:
Act 1.1 – Synthesis and characterization of carboxymethyl chitosan (CMCS)
Act 1.2 – Conjugation of CMCS with CGSPGWVRC and indolicidin peptides
Act 1.3 – Synthesis and characterization of fluorescein-labeled CMCS
The obtained materials were characterized from several points of view for the correct correlation of the properties with the synthesis parameters.
During stage II entitled: “Design and synthesis of peptides-functionalized nano / microparticles (2PEP-N / MPs)” several activities were carried out as follows:
Act 2.1 – Preparation of nano/microspheres functionalized with peptides
Act 2.2 – Preparation of nano/microcapsules functionalized with peptides
Two types of peptide-functionalized particles, nano/microsphere and nano/microcapsules, were prepared.