{"id":5673,"date":"2022-11-17T17:24:17","date_gmt":"2022-11-17T17:24:17","guid":{"rendered":"https:\/\/velea.ro\/univapollonia\/?page_id=5673"},"modified":"2023-02-17T05:23:17","modified_gmt":"2023-02-17T05:23:17","slug":"nanoforbcc-project-summary","status":"publish","type":"page","link":"https:\/\/www.univapollonia.ro\/en\/nanoforbcc-project-summary\/","title":{"rendered":"NANOforBCC \u2013 project summary"},"content":{"rendered":"<p>[vc_row][vc_column width=&#8221;1\/4&#8243;]<div class=\"widget_sidebar_menu main-sidebar-menu\"><div class=\"sidebar-menu-wrap\"><ul id=\"menu-nanoforbcc-en\" class=\"sidebar-menu\"><li id=\"nav-menu-item-6589\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children  has-sub narrow \"><a href=\"https:\/\/www.univapollonia.ro\/en\/nanoforbcc\/\">NANOforBCC<\/a><span class=\"arrow\"><\/span>\n<div class=\"popup\"><div class=\"inner\" style=\"\"><ul class=\"sub-menu\">\n\t<li id=\"nav-menu-item-6595\" class=\"menu-item menu-item-type-post_type menu-item-object-page \" data-cols=\"1\"><a href=\"https:\/\/www.univapollonia.ro\/en\/nanoforbcc-project-summary\/\">NANOforBCC \u2013 project summary<\/a><\/li>\n\t<li id=\"nav-menu-item-6592\" class=\"menu-item menu-item-type-post_type menu-item-object-page \" data-cols=\"1\"><a href=\"https:\/\/www.univapollonia.ro\/en\/nanoforbcc\/nanoforbcc-objectives-and-activities-of-the-project\/\">NANOforBCC \u2013 objectives and activities of the project<\/a><\/li>\n\t<li id=\"nav-menu-item-6593\" class=\"menu-item menu-item-type-post_type menu-item-object-page \" data-cols=\"1\"><a href=\"https:\/\/www.univapollonia.ro\/en\/nanoforbcc\/nanoforbcc-project-team\/\">NANOforBCC \u2013 project team<\/a><\/li>\n\t<li id=\"nav-menu-item-6594\" class=\"menu-item menu-item-type-post_type menu-item-object-page \" data-cols=\"1\"><a href=\"https:\/\/www.univapollonia.ro\/en\/nanoforbcc\/nanoforbcc-results\/\">NANOforBCC \u2013 results<\/a><\/li>\n\t<li id=\"nav-menu-item-6591\" class=\"menu-item menu-item-type-post_type menu-item-object-page \" data-cols=\"1\"><a href=\"https:\/\/www.univapollonia.ro\/en\/nanoforbcc\/nanoforbcc-dissemination\/\">NANOforBCC \u2013 dissemination<\/a><\/li>\n\t<li id=\"nav-menu-item-6590\" class=\"menu-item menu-item-type-post_type menu-item-object-page \" data-cols=\"1\"><a href=\"https:\/\/www.univapollonia.ro\/en\/nanoforbcc\/nanoforbcc-contact\/\">NANOforBCC \u2013 contact<\/a><\/li>\n<\/ul><\/div><\/div>\n<\/li>\n<\/ul><\/div><\/div>[\/vc_column][vc_column width=&#8221;3\/4&#8243;][vc_column_text]Cancer targeted therapy is a treatment that targets the cancer\u2019s specific genes, proteins, or the tissue environment that contributes to cancer growth and survival and blocks the growth and the spread of cancer cells while limiting damage to healthy cells. In order to minimize the impact of systemic toxicity of the anti-cancer drugs, the achievement of reliable and efficient delivery systems of therapeutics is necessary. In this context, nanoscale biomedical engineering can provide efficient drug delivery systems for the skin cancers, current project enrolling in this research direction, with the purpose to obtain new formulations based on nanoparticulate systems capable to include, transport and release anti-tumor drugs specific to skin cancer (BCC) in a sustained\/controlled manner. The original approach of this project has not only the advantage of targeting specifically the tumor cells and, consequently, to increase the efficiency of the treatment by releasing antitumoral drugs directly to the site of disease but also to increase the patient compliance. Studies will be performed to confirm the potential application of obtained drug-delivery systems in the treatment of BCC, such as: evaluation of nanoparticles drug loading,\u00a0<em>in vitro<\/em>\u00a0skin permeation studies,\u00a0<em>in vitro<\/em>\u00a0cytotoxicity, skin irritation potential,\u00a0<em>in vitro<\/em>\u00a0targeting capability and apoptotic effects. The experimental experience of the project leader\u2013confirmed by numerous papers published in journals of wide international circulation \u2013 is a guarantee of solving the objectives of this project.[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column width=&#8221;1\/4&#8243;][\/vc_column][vc_column width=&#8221;3\/4&#8243;][vc_column_text]Cancer targeted therapy is a treatment that targets the cancer\u2019s specific genes, proteins, or the tissue environment that contributes to cancer growth and survival and blocks the growth and the spread of cancer cells while limiting damage to healthy cells. In order to minimize the impact of systemic toxicity of the anti-cancer drugs, [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"inline_featured_image":false,"footnotes":""},"class_list":["post-5673","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.univapollonia.ro\/en\/wp-json\/wp\/v2\/pages\/5673","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.univapollonia.ro\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.univapollonia.ro\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.univapollonia.ro\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.univapollonia.ro\/en\/wp-json\/wp\/v2\/comments?post=5673"}],"version-history":[{"count":3,"href":"https:\/\/www.univapollonia.ro\/en\/wp-json\/wp\/v2\/pages\/5673\/revisions"}],"predecessor-version":[{"id":6613,"href":"https:\/\/www.univapollonia.ro\/en\/wp-json\/wp\/v2\/pages\/5673\/revisions\/6613"}],"wp:attachment":[{"href":"https:\/\/www.univapollonia.ro\/en\/wp-json\/wp\/v2\/media?parent=5673"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}