{"id":6119,"date":"2023-02-05T21:45:57","date_gmt":"2023-02-05T21:45:57","guid":{"rendered":"https:\/\/velea.ro\/univapollonia\/?page_id=6119"},"modified":"2023-02-17T05:32:00","modified_gmt":"2023-02-17T05:32:00","slug":"hynanofab-objectives-and-activities-of-the-project","status":"publish","type":"page","link":"https:\/\/www.univapollonia.ro\/en\/hynanofab-general-information\/hynanofab-objectives-and-activities-of-the-project\/","title":{"rendered":"HYnanoFAB \u2013 objectives and activities of the project"},"content":{"rendered":"<p>[vc_row][vc_column width=&#8221;1\/4&#8243;]<div class=\"widget_sidebar_menu main-sidebar-menu\"><div class=\"sidebar-menu-wrap\"><ul id=\"menu-hynanofab-en\" class=\"sidebar-menu\"><li id=\"nav-menu-item-6624\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children  has-sub narrow \"><a href=\"https:\/\/www.univapollonia.ro\/en\/hynanofab-general-information\/\">HYnanoFAB \u2013 General information<\/a><span class=\"arrow\"><\/span>\n<div class=\"popup\"><div class=\"inner\" style=\"\"><ul class=\"sub-menu\">\n\t<li id=\"nav-menu-item-6625\" class=\"menu-item menu-item-type-post_type menu-item-object-page \" data-cols=\"1\"><a href=\"https:\/\/www.univapollonia.ro\/en\/hynanofab-general-information\/hynanofab-project-summary\/\">HYnanoFAB \u2013 project summary<\/a><\/li>\n\t<li id=\"nav-menu-item-6626\" class=\"menu-item menu-item-type-post_type menu-item-object-page \" data-cols=\"1\"><a href=\"https:\/\/www.univapollonia.ro\/en\/hynanofab-general-information\/hynanofab-objectives-and-activities-of-the-project\/\">HYnanoFAB \u2013 objectives and activities of the project<\/a><\/li>\n\t<li id=\"nav-menu-item-6627\" class=\"menu-item menu-item-type-post_type menu-item-object-page \" data-cols=\"1\"><a href=\"https:\/\/www.univapollonia.ro\/en\/hynanofab-general-information\/hynanofab-team-members\/\">HYnanoFAB \u2013 team members<\/a><\/li>\n\t<li id=\"nav-menu-item-6628\" class=\"menu-item menu-item-type-post_type menu-item-object-page \" data-cols=\"1\"><a href=\"https:\/\/www.univapollonia.ro\/en\/hynanofab-general-information\/hynanofab-results\/\">HYnanoFAB \u2013 results<\/a><\/li>\n\t<li id=\"nav-menu-item-6629\" class=\"menu-item menu-item-type-post_type menu-item-object-page \" data-cols=\"1\"><a href=\"https:\/\/www.univapollonia.ro\/en\/hynanofab-general-information\/hynanofab-diseminare\/\">HYnanoFAB \u2013 diseminare<\/a><\/li>\n\t<li id=\"nav-menu-item-6630\" class=\"menu-item menu-item-type-post_type menu-item-object-page \" data-cols=\"1\"><a href=\"https:\/\/www.univapollonia.ro\/en\/hynanofab-general-information\/hynanofab-contact\/\">HYnanoFAB \u2013 contact<\/a><\/li>\n<\/ul><\/div><\/div>\n<\/li>\n<\/ul><\/div><\/div>[\/vc_column][vc_column width=&#8221;3\/4&#8243;][vc_column_text]<\/p>\n<div id=\"the-content\">\n<p><strong>Project objectives<\/strong><\/p>\n<p>The general objective of this project is to develop new antibacterial biocomposite hydrogels containing zinc oxide nanoparticles and Curcumin-loaded electrospun nanofibers able to enhance the effectiveness of wound healing process caused by burns. The research studies will be divided into several secondary objectives, all subordinated to the main objective: i) preparation by co-axial electrospinning method of a new type of Curcumin-loaded nanofibers; ii) the preparation of hydrogels based on hyaluronic acid (HA) and sodium alginate (AG) containing zinc oxide nanoparticles (ZnO NPs); iii) the preparation and physico-chemical characterization of the biocomposite hydrogels containing ZnO NPs and Curcumin-loaded nanofibers (HZ-NFC); iv) the in vitro evaluation of biodegradability, hemocompatibility, cytotoxicity, skin irritation potential and antimicrobial activity of both nanofibers and biocomposite hydrogels.<\/p>\n<p><strong>Project activities<\/strong><\/p>\n<p>A1: Design, preparation and characterization of curcumin-loaded nanofibers<\/p>\n<p>A2: Design, preparation and characterization of biocomposite hydrogel containing ZnO NPs<\/p>\n<p>(HZ).<\/p>\n<p>A3: Preparation and characterization of biocomposite hydrogel containing ZnO NPs and curcumin-loaded nanofibers (HZ-NFC) and\u00a0<em>in vitro<\/em>\u00a0release and skin permeation studies of curcumin<\/p>\n<p>A4: Evaluation of the biomaterial properties of the curcumin-loaded nanofibers (NFC), biocomposite hydrogel type HZ and biocomposite hydrogel type HZ-NFC<\/p>\n<p>A5: Antimicrobial activity of NFC, HZ and biocomposite hydrogel type HZ-NFC and optimization and selection of biocomposite hydrogels.<\/p>\n<\/div>\n<p>[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column width=&#8221;1\/4&#8243;][\/vc_column][vc_column width=&#8221;3\/4&#8243;][vc_column_text] Project objectives The general objective of this project is to develop new antibacterial biocomposite hydrogels containing zinc oxide nanoparticles and Curcumin-loaded electrospun nanofibers able to enhance the effectiveness of wound healing process caused by burns. The research studies will be divided into several secondary objectives, all subordinated to the main objective: i) [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":6115,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"inline_featured_image":false,"_joinchat":[],"footnotes":""},"class_list":["post-6119","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.univapollonia.ro\/en\/wp-json\/wp\/v2\/pages\/6119","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.univapollonia.ro\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.univapollonia.ro\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.univapollonia.ro\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.univapollonia.ro\/en\/wp-json\/wp\/v2\/comments?post=6119"}],"version-history":[{"count":3,"href":"https:\/\/www.univapollonia.ro\/en\/wp-json\/wp\/v2\/pages\/6119\/revisions"}],"predecessor-version":[{"id":6633,"href":"https:\/\/www.univapollonia.ro\/en\/wp-json\/wp\/v2\/pages\/6119\/revisions\/6633"}],"up":[{"embeddable":true,"href":"https:\/\/www.univapollonia.ro\/en\/wp-json\/wp\/v2\/pages\/6115"}],"wp:attachment":[{"href":"https:\/\/www.univapollonia.ro\/en\/wp-json\/wp\/v2\/media?parent=6119"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}